Avian Influenza (AI) remains a serious threat to the poultry industry in Indonesia. The rainy season, occurring from October to March, is characterized by high temperatures and humidity, as well as increased migratory bird activity. These factors cause more frequent AI outbreaks and result in significant economic losses. Conventional prevention efforts are generally high-cost and carry the risk of drug resistance. The synergistic application of Eucommia leaf extract and bile acids offers a safe and efficient solution. This article discusses key prevention steps and practical product application.

Primary Symptoms for Identification (Keys to Early Detection)

• Sudden death.

• Respiratory distress (rales/snoring, coughing).

• Swelling and purplish discoloration of the comb, wattles, and shanks (legs).

• Lethargy, loss of appetite, and diarrhea.

• Drop in egg production and an increase in soft-shelled or misshapen eggs.

I. Primary Prevention: Strengthening Biosecurity

Biosecurity is the first line of defense during the rainy season to break the chain of virus transmission through targeted control measures:

1. Personnel and Vehicle Control:

• Implement a closed-house system.

• Restrict entry and movement between farms.

• Disinfect vehicles before they enter the farm area and separate loading/unloading zones.

2. Cleaning and Disinfection:

• Perform disinfection 2–3 times per week (daily during high-risk periods).

• Implement standard operating procedures (SOPs) for the handling of feces and carcasses.

3. Control of Wild Birds and Pests:

• Install safety netting and drain standing water.

• Strengthen rodent and insect control to prevent disease transmission.

4. Precise and Scientific Vaccination:

• Develop vaccination programs based on locally circulating virus subtypes.

• Allow a minimum interval of 2 hours between vaccination and product administration.

5. Training and Monitoring:

• Provide routine training for farm workers.

• Conduct daily livestock inspections.

• Immediately isolate birds showing abnormal symptoms.

II. Efficient Prevention and Control: Synergistic Application of Core Products

The synergistic use of Eucommia leaf extract and bile acids has proven to be safe, effective, and non-resistant, meeting the needs of Indonesian farmers for low-cost and sustainable prevention and control systems.

(I) Core Products and Mechanisms of Action

Happiness Feed Eucommia ulmoides P.E. Contains active compounds such as chlorogenic acid (≥5%), flavonoids (≥8%), and polysaccharides (≥20%) with the following primary benefits:

• Immune Enhancement: Activates immune cells and increases livestock resistance to stress.

• Antiviral: Inhibits the attachment and replication process of the virus.

• Anti-stress and Antioxidant: Reduces the negative impacts of high temperature, humidity, and viral infection while protecting internal organs.

RUNEON Bile Acids A natural metabolic regulator that works synergistically with Eucommia leaf extract, functioning to:

• Enhance Nutrient Absorption: Improves the absorption of fats and fat-soluble vitamins, indirectly strengthening the immune system.

• Protect the Intestinal Barrier: Suppresses inflammation and reduces the risk of secondary infections.

• Synergistic Antiviral Effect: Damages the viral envelope and strengthens the effectiveness of disease prevention and control.

(II) Dosage Recommendations (Mixed in Feed, per Ton)

• Routine Prevention (During the rainy season):

  • Eucommia leaf extract: 150–250 g + Bile acids: 200 g

• High-Risk Period / Suspected Infection:

  • Eucommia leaf extract: 250–300 g + Bile acids: 200 g (Use continuously for 10–15 days).